High chemokine ligand 11 levels in nasal lavage fluid: A potential predictor of and therapeutic target for murine eosinophilic chronic rhinosinusitis
X Ren, Z Wang - Life Sciences, 2021 - Elsevier
Aim We aimed to discover whether group 2 innate lymphoid cells (ILC2s) and cytokines in
nasal lavage fluid could be used to predict eosinophilic infiltration in mice with eosinophilic
chronic rhinosinusitis (ECRS). Methods Ten mice were divided into two groups. The ECRS
group received an intranasal challenge of Aspergillus oryzae protease (AP) and ovalbumin
(OVA) to establish disease. A control group received intranasal phosphate-buffered saline.
Histopathology of nasal cavities and paranasal sinuses, and cytokine and ILC2s levels in …
nasal lavage fluid could be used to predict eosinophilic infiltration in mice with eosinophilic
chronic rhinosinusitis (ECRS). Methods Ten mice were divided into two groups. The ECRS
group received an intranasal challenge of Aspergillus oryzae protease (AP) and ovalbumin
(OVA) to establish disease. A control group received intranasal phosphate-buffered saline.
Histopathology of nasal cavities and paranasal sinuses, and cytokine and ILC2s levels in …
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